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Peer-reviewed veterinary case report

Canine diabetes mellitus risk factors: A matched case-control study.

Journal:
Research in veterinary science
Year:
2017
Authors:
Pöppl, Alan Gomes et al.
Affiliation:
Departamento de Medicina Animal · Brazil
Species:
dog

Plain-English summary

This study looked at the risk factors for diabetes in dogs, specifically focusing on 110 diabetic dogs and 136 healthy dogs that were similar in breed, sex, and age. The researchers found that dogs that were overweight or not fed a balanced commercial diet were at a higher risk of developing diabetes. Additionally, female dogs that were given table scraps or were in a specific reproductive stage called diestrus (the period after a female dog has come into heat) also showed increased risk. These findings suggest that certain feeding habits and weight management are important for preventing diabetes in dogs. Overall, the study highlights the importance of proper diet and weight control in reducing the risk of diabetes in dogs.

Abstract

Different subtypes of canine diabetes mellitus (CDM) have been described based on their aetiopathogenesis. Therefore, manifold risk factors may be involved in CDM development. This study aims to investigate canine diabetes mellitus risk factors. Owners of 110 diabetic dogs and 136 healthy controls matched by breed, sex, and age were interviewed concerning aspects related to diet, weight, physical activity, oral health, reproductive history, pancreatitis, and exposure to exogenous glucocorticoids. Two multivariate multivariable statistical models were created: The UMod included males and females without variables related to oestrous cycle, while the FMod included only females with all analysed variables. In the UMod, "Not exclusively commercial diet" (OR 4.86, 95%CI 2.2-10.7, P<0.001) and "Overweight" (OR 3.51, 95%CI 1.6-7.5, P=0.001) were statistically significant, while in the FMod, "Not exclusively commercial diet" (OR 4.14, 95%CI 1.3-12.7, P=0.01), "Table scraps abuse" (OR 3.62, 95%CI 1.1-12.2, P=0.03), "Overweight" (OR 3.91, 95%CI 1.2-12.6, P=0.02), and "Dioestrus" (OR 5.53, 95%CI 1.9-16.3, P=0.002) were statistically significant. The findings in this study support feeding not exclusively balanced commercial dog food, overweight, treats abuse, and diestrus, as main CDM risk factors. Moreover, those results give subside for preventive care studies against CDM development.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/28802947/