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Peer-reviewed veterinary case report

Dog with immune-mediated diabetes and anemia treated with insulin

By Elie, M & Hoenig, M·Published in Journal of the American Animal Hospital Association·1995·School of Veterinary Medicine, United States·View original on PubMed

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Original publication title: Canine immune-mediated diabetes mellitus: a case report.

Species:
dog

Plain-English summary

A 4-year-old spayed female toy fox terrier was brought to the vet because she had high blood sugar and severe anemia. After testing, the vet diagnosed her with immune-mediated diabetes mellitus, which means her immune system was attacking the cells that produce insulin, and immune-mediated hemolytic anemia, where her body was destroying its own red blood cells. The anemia improved after two months of treatment with immunosuppressive medication, and she was able to stop insulin treatment after four months, although she still tested positive for antibodies that could indicate diabetes might return later.

People also search for: toy fox terrier diabetes treatment · dog anemia symptoms · immune-mediated diabetes in dogs

Abstract

A four-year-old, spayed female toy fox terrier presented with hyperglycemia and severe anemia. A diagnosis of immune-mediated diabetes mellitus was made based upon the finding of beta-cell specific antibodies. Immune-mediated hemolytic anemia was diagnosed based on findings of a regenerative anemia, spherocytosis, hyperbilirubinemia, hemoglobinuria, and bilirubinuria. The anemia resolved following two months of immunosuppressive therapy. The diabetes was treated with insulin for four months, after which time treatment was no longer necessary. However, the dog remained positive for beta-cell antibodies which may be a predictive marker for the recurrence of diabetes mellitus in the future.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7552660/