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Peer-reviewed veterinary case report

Insulin-secreting β-cell neoplasia in a 7-year-old female dog, case report and review

Journal:
Cogent Food & Agriculture
Year:
2017
Authors:
Edwin Aihanuwa Uwagie-Ero et al.
Affiliation:
University of Benin · GB
Species:
dog

Plain-English summary

A 7-year-old female dog was having problems like leaking urine, shaking, weakness in her back legs, and being very tired over the course of two months. The vet suspected she had low blood sugar due to a tumor in her pancreas that was producing insulin. To treat this, the dog underwent surgery to remove the tumor, but afterward, she developed pancreatitis, which is inflammation of the pancreas. A closer examination of the tumor showed it was a malignant (cancerous) growth. The treatment aimed to address the insulin-secreting tumor, but the dog faced significant complications after surgery.

Abstract

A 7-year-old female dog presented with intermittent episodes of urinary incontinence, tremors, intermittent episodes of pelvic limb weakness and collapse, and lethargy were noticed over a period of two months. Hypoglycaemia, secondary to an insulin-secreting β-cell tumour, was suspected on the basis of clinical signs, ultrasound and serum biochemistry. A laparotomy was then performed to remove the tumour mass. Post-surgical pancreatitis was a major complication. Histology revealed a malignant neuroendocrine neoplasia of the β-cells of the pancreas. This case review is reported to keep clinicians abreast of the canine insulinoma disorder and the complications surrounding its diagnosis and treatment.

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Original publication: https://doi.org/10.1080/23311932.2017.1293467