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Peer-reviewed veterinary case report

Carcinoma of the mammary gland in a mare.

Journal:
Journal of the American Veterinary Medical Association
Year:
1987
Authors:
Munson, L
Species:
horse

Plain-English summary

A 17-year-old Quarter Horse mare had serious health issues, including swelling in both mammary glands, fluid buildup in her belly, trouble breathing, and signs of neurological problems. Unfortunately, she was euthanized, and a type of cancer called carcinoma was found in her mammary glands during the examination after her death. The cancer had spread to many other organs and parts of her body, including her muscles and nervous system. The tumor was made up of abnormal cells that replaced the normal tissue in her mammary glands. Sadly, the treatment options were not effective, as the mare's condition was too advanced.

Abstract

A 17-year-old Quarter Horse mare developed rapidly progressive, bilateral, firm enlargements of both mammary glands, ventral abdominal edema, dyspnea, and neurologic signs. The horse was euthanatized, and a carcinoma of the mammary gland was diagnosed at necropsy. Microscopically, normal glandular parenchyma was replaced by neoplastic nodules, and the tumor had metastasized to most visceral organs and throughout the musculoskeletal and central nervous systems. The tumor had a solid pattern, with microglandular differentiation, and numerous syncytial sheets.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/3610781/