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Peer-reviewed veterinary case report

Chromosome changes found in thyroid tumor of 14-year-old German

By Mayr, B et al.·Published in Research in veterinary science·1991·Institute of Animal Breeding and Genetics·View original on PubMed

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Original publication title: Characterisation of complex karyotype changes in a canine thyroid adenoma.

Species:
dog

Plain-English summary

A 14-year-old German shepherd was diagnosed with a thyroid tumor called an alveolar adenoma after showing signs of illness. Tests on the tumor cells revealed unusual changes in the dog's chromosomes, indicating a complex genetic alteration. While the study focused on the genetic details of the tumor, it highlights the importance of veterinary evaluation for older dogs showing health issues. Treatment options for thyroid tumors in dogs can vary, so it's essential to discuss the best approach with your veterinarian.

People also search for: dog thyroid tumor symptoms · German shepherd cancer treatment · older dog health issues

Abstract

A 14-year-old German shepherd dog developed an alveolar adenoma of the thyroid. The cytogenetic evaluation of the tumour cells showed two ranges of chromosome numbers. Centric fusions 2/32, 5/26, 6/11, 8/11, 9/23 and 14/31 were G-band identified in this complex change of karyotype.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1882136/