Peer-reviewed veterinary case report
Chronic stomach and intestine inflammation causing weight loss
By Cervone, Mario et al.·Published in Brazilian Journal of Veterinary Pathology·2017·View original on Crossref →
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Original publication title: Chronic gastrointestinal inflammation in a dog mimicking human russell body gastroduodenitis
- Species:
- dog
Plain-English summary
A 10-year-old Golden Retriever was brought in for chronic weight loss, vomiting, diarrhea, and unusual eating behavior (pica). Blood tests showed low protein levels, and biopsies of the stomach and intestines revealed a type of inflammation similar to a condition seen in humans. The dog was treated with medications to reduce stomach acid, antibiotics, and corticosteroids. After treatment, the dog's gastrointestinal symptoms improved, and there were no signs of recurrence.
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Abstract
Herein we describe an unusual benign chronic gastroduodenal inflammation associated with protein losing enteropathy in a dog. A 10-year-old Golden Retriever dog was presented for chronic weight loss associated with pica, ptyalism, vomiting and diarrhea. Blood chemistry showed hypoproteinaemia and hypoalbuminaemia. Gastric and duodenal full-thickness biopsies were collected and histopathological examination revealed severe mucosal infiltration with Mott cells, consistent with Russell body gastroduodenitis in humans. Warthin-starry stain showed no Helicobacter spp. proliferation in gastric biopsies. After treatment including anti-acid, antibiotics and corticosteroids, no recurrence of gastrointestinal signs was reported and improvement in clinical and biological condition was observed.
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Search related cases →Original publication on Crossref: https://doi.org/10.24070/bjvp.1983-0246.v10i3p100-104