Peer-reviewed veterinary case report
Chronic gastrointestinal inflammation in a dog mimicking human russell body gastroduodenitis
- Journal:
- Brazilian Journal of Veterinary Pathology
- Year:
- 2017
- Authors:
- Cervone, Mario et al.
- Species:
- dog
Plain-English summary
A 10-year-old Golden Retriever was brought to the vet because he was losing weight and had been eating non-food items, drooling, vomiting, and having diarrhea. Blood tests showed low protein levels. The vet took samples from the dog's stomach and upper intestine, which showed a type of inflammation similar to a condition seen in humans. After treatment with medications to reduce stomach acid, antibiotics, and steroids, the dog did not have any more gastrointestinal problems, and his overall health improved.
Abstract
Herein we describe an unusual benign chronic gastroduodenal inflammation associated with protein losing enteropathy in a dog. A 10-year-old Golden Retriever dog was presented for chronic weight loss associated with pica, ptyalism, vomiting and diarrhea. Blood chemistry showed hypoproteinaemia and hypoalbuminaemia. Gastric and duodenal full-thickness biopsies were collected and histopathological examination revealed severe mucosal infiltration with Mott cells, consistent with Russell body gastroduodenitis in humans. Warthin-starry stain showed no Helicobacter spp. proliferation in gastric biopsies. After treatment including anti-acid, antibiotics and corticosteroids, no recurrence of gastrointestinal signs was reported and improvement in clinical and biological condition was observed.
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Search related cases →Original publication: https://doi.org/10.24070/bjvp.1983-0246.v10i3p100-104