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Peer-reviewed veterinary case report

Painful swollen mammary tumor with ulcers in a 13-year-old dog

By Salgado, Breno S et al.·Published in Veterinary clinical pathology·2013·Departamento de Patologia, Brazil·View original on PubMed

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Original publication title: Clinical, cytologic, and histologic features of a mammary micropapillary carcinoma in a dog.

Species:
dog

Plain-English summary

A 13-year-old female mongrel dog was brought in with severe pain, swelling, and redness in the mammary area, along with skin ulcers. Tests showed she had a rare type of breast cancer called micropapillary carcinoma, which had spread to her lymph nodes and other organs. Despite surgery to remove the affected mammary tissue, her condition worsened over the next five months. Unfortunately, the dog was euthanized due to her deteriorating health, and a post-mortem examination confirmed that the cancer had spread extensively throughout her body.

People also search for: dog breast cancer symptoms · mammary tumor treatment in dogs · what to expect after dog mastectomy

Abstract

Mammary invasive micropapillary carcinoma is a rare variant of mammary carcinoma that was recently recognized in dogs. The cytologic features and biologic behavior of such neoplasms in dogs have not yet been widely discussed in the veterinary literature. We report the clinical, cytologic, and histologic features of a canine micropapillary carcinoma in a 13-year-old female mongrel dog. The mammary region presented with extreme local pain, severe edema and erythema, and multifocal epidermal ulceration, which is typical for an inflammatory mammary carcinoma. Fine-needle aspirates were highly cellular and consisted of individual cells and papillary cell clusters with characteristics of malignant epithelial cells. Histologic examination revealed neoplastic cells arranged in small papillae without fibrovascular cores, sometimes inside clear lymphatic spaces, indicating lymphovascular invasion. Regional lymph node evaluation revealed metastatic cells. Due to deteriorating clinical condition the dog was euthanatized 5 months after mastectomy. At necropsy, metastatic neoplastic mammary cells were found in popliteal and mediastinal lymph nodes, the right femoral biceps muscle, liver, heart, lungs, and urinary bladder.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23919629/