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Peer-reviewed veterinary case report

Rottweiler puppy with rare blood disorder and seizures gets better

By James, F E & Mansfield, C S·Published in Australian veterinary journal·2009·Murdoch University, Australia·View original on PubMed

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Original publication title: Clinical remission of idiopathic hypereosinophilic syndrome in a Rottweiler.

Species:
dog

Plain-English summary

A 6-month-old female Rottweiler had seizures after a traumatic incident and was found to have a rare condition called idiopathic hypereosinophilic syndrome (HES), which caused high levels of a type of white blood cell and liver problems. After thorough testing, no specific cause was identified, but the dog's condition improved on its own, and her liver function returned to normal. Remarkably, she is still alive and healthy over four years later. This case suggests that HES in Rottweilers may not always lead to a poor outcome and can resolve without treatment.

People also search for: Rottweiler seizures treatment · dog liver problems · idiopathic hypereosinophilic syndrome in dogs

Abstract

Idiopathic hypereosinophilic syndrome (HES) is a rare syndrome for which Rottweilers appear to over-represent the canine cases. A 6-month-old female entire Rottweiler presented with seizures following a traumatic incident. The dog was identified as having a marked, sustained eosinophilia and investigations did not identify an underlying cause. Concurrently, the dog had chronic eosinophilic hepatitis with impaired liver function and mesenteric eosinophilic lymphadenitis. The dog went on to have spontaneous resolution of HES and normal liver function was subsequently documented. To date, the dog is still alive, more than 4 years after initial presentation. The diagnosis of idiopathic HES in Rottweilers may not carry a poor prognosis and the condition may spontaneously resolve, even in cases with documented organ damage.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19673849/