Peer-reviewed veterinary case report
Using cyclosporine with steroids to treat cats with pure red cell
By Viviano, Katrina R & Webb, Julie L·Published in Journal of feline medicine and surgery·2011·Department of Medical Sciences, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Clinical use of cyclosporine as an adjunctive therapy in the management of feline idiopathic pure red cell aplasia.
- Species:
- cat
Plain-English summary
A group of 10 cats with a serious blood condition called idiopathic pure red cell aplasia (PRCA) were treated with a combination of steroids and a medication called cyclosporine. Out of these cats, 8 showed improvement and were able to stay in remission for an average of about 31 days, with some maintaining remission for over a year. While many cats needed to continue on a low dose of the medication to prevent relapse, some were able to stop treatment altogether. If any side effects occurred from the cyclosporine, they were usually manageable by adjusting the dose. Overall, this combination therapy was effective in helping these cats recover from PRCA.
People also search for: cat blood condition treatment · cyclosporine for cats · feline pure red cell aplasia symptoms
Abstract
The clinical use of cyclosporine is described in a group of client-owned cats diagnosed with idiopathic pure red cell aplasia (PRCA). All 10 cats were treated with combinations of glucocorticoids and cyclosporine. Of the 10 cats, the eight for which follow-up data was available achieved and maintained remission for a median of 31 and 406 days, respectively. Therapy was reduced or discontinued in 7/8 cats; 2/7 maintained remission off therapy and 5/7 cats relapsed. Remission was reinduced in four cats, with 3/4 cats maintained long-term on low dose therapy. Adverse effects associated with cyclosporine therapy were responsive to dose reduction or drug withdrawal. Feline idiopathic PRCA was responsive to combination immunosuppressive therapy with glucocorticoids and cyclosporine. Relapse was common, particularly after drug discontinuation; therefore, most cats required maintenance long-term low dose therapy.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21900029/