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Peer-reviewed veterinary case report

Dog with rare mammary liposarcoma and ovarian tumor co-occurrence

By Polinas, M et al.·Published in Research in veterinary science·2016·Department of Veterinary Medicine, Italy·View original on PubMed

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Original publication title: Co-occurrence of a metastatic mammary liposarcoma and an ovarian sex-cord stromal tumor in a dog.

Species:
dog

Plain-English summary

A 14-year-old female poodle was brought in with a mammary mass that was diagnosed as a rare type of tumor called pleomorphic liposarcoma. After surgery to remove the tumor, it came back two years later, and this time it had spread to nearby lymph nodes. During the examination, the vet also found a separate tumor in the dog's ovary. Both tumors tested positive for hormone receptors, which can influence their growth. This case highlights the unusual occurrence of these two types of tumors in the same dog, and it emphasizes the importance of monitoring for recurrences after surgery.

People also search for: dog mammary tumor treatment · poodle ovarian tumor symptoms · metastatic liposarcoma in dogs

Abstract

Sarcoma arising in the mammary gland is a rare tumor in dogs, and primary liposarcoma with metastatic behavior has never been previously reported among canine mammary tumors. A 14-year old female poodle had a mammary mass diagnosed as pleomorphic liposarcoma. Two years following surgical removal, the tumor recurred in the mammary gland with lymph node metastases. In addition, a sex-cord stromal tumor was identified in the ovary. Immunohistochemistry was performed on both tumors that were positive for oestrogen and progesterone receptors. Moreover, the ovarian tumor was positive for calretinin. This is the first report to the authors' knowledge, of the co-occurrence of a pleomorphic liposarcoma of the mammary gland and an ovarian sex-cord stromal (gonadostromal) tumor in the dog.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27892865/