Peer-reviewed veterinary case report
Persistent Mullerian duct syndrome and testicular tumors in male dogs
By Park, Eun Jung et al.·Published in BMC veterinary research·2017·College of Veterinary Medicine and the Research Institute of Veterinary Science, South Korea·View original on PubMed →
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Original publication title: Coincidence of Persistent Müllerian duct syndrome and testicular tumors in dogs.
- Species:
- dog
Plain-English summary
A 7-year-old male Maltese and a 17-year-old male mixed-breed dog were both diagnosed with a rare condition called Persistent Müllerian duct syndrome (PMDS), which can lead to abnormal sexual development and is often associated with undescended testicles (cryptorchidism). Both dogs had enlarged prostates and elevated hormone levels, and they underwent surgery to remove the testicular tumors and any related tissue. Early diagnosis and treatment are crucial, as it can help prevent tumors from developing in dogs with cryptorchidism.
People also search for: Maltese dog testicular tumor · cryptorchidism in dogs · PMDS in dogs treatment
Abstract
BACKGROUND: Persistent Müllerian duct syndrome (PMDS), a rare form of male pseudohermaphroditism in dogs, is an abnormal sexual phenotype in males that is characterized by the existence of a hypoplastic oviduct, uterus, and cranial part of the vagina. Dogs suffering from PMDS are often accompanied by cryptorchidism. To date, it has been mainly found in the Miniature Schnauzer breed. CASE PRESENTATION: In this report, two cases of PMDS with a malignant testicular tumor originating from cryptorchidism in breeds other than the Miniature Schnauzer breed are described. The patients were a seven-year-old male Maltese dog and a 17-year-old male mixed-breed dog weighing 3.8 kg. They also exhibited an enlarged prostate with or without abscess and an elevated serum estradiol level and were surgically treated to remove the testicular tumor and Müllerian duct derivatives. CONCLUSIONS: It is recommended that PMDS should be differentially diagnosed by ultrasonography and that orchiectomy be performed at an early age in patients suspected to have cryptorchidism to prevent the ectopic testes from becoming tumorous.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28576146/