Peer-reviewed veterinary case report
Clotrimazole flush and cream treat nasal aspergillosis in dogs
By Sissener, T R et al.·Published in The Journal of small animal practice·2006·The Queen's Veterinary School Hospital, United Kingdom·View original on PubMed →
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Original publication title: Combined clotrimazole irrigation and depot therapy for canine nasal aspergillosis.
- Species:
- dog
Plain-English summary
A group of 14 dogs with nasal aspergillosis, a fungal infection affecting their sinuses, underwent a new treatment involving a quick flush of a clotrimazole solution followed by a cream application. Most dogs, 12 out of 14, showed significant improvement, with many having no symptoms after treatment or only mild signs of rhinitis (nasal inflammation) during follow-up. The procedure was well-tolerated, with minimal complications, and it required less time under anesthesia compared to previous methods. This approach appears to be an effective option for treating nasal aspergillosis in dogs.
People also search for: dog nasal infection treatment · clotrimazole for dogs · nasal aspergillosis symptoms in dogs
Abstract
OBJECTIVES: To evaluate the effect of short duration 1 per cent clotrimazole flush when combined with 1 per cent clotrimazole cream instilled into the frontal sinuses for the treatment of nasal aspergillosis in 14 dogs. METHODS: Fourteen dogs with clinical, radiological, serological and rhinoscopic findings consistent with nasal aspergillosis were treated by frontal sinus trephination and a short, five-minute flushing of 1 per cent topical clotrimazole solution followed by a 1 per cent clotrimazole cream instilled as a depot agent. RESULTS: Twelve of the 14 dogs (86 per cent) responded well to treatment and either had no clinical signs after treatment or had signs consistent with mild rhinitis during a minimum follow-up period of six months. Only one dog required multiple treatments. Treatment was well tolerated by all patients, with minimal complications. CLINICAL SIGNIFICANCE: This treatment compares favourably to previously published data using one-hour topical clotrimazole or enilconazole flushing treatment protocols. The treatment technique significantly reduced treatment time under anaesthesia.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16761982/