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Peer-reviewed veterinary case report

Complex mammary gland tumor with sebaceous cells in a dog

By Kurilj, A G et al.·Published in Journal of comparative pathology·2012·Department of Veterinary Pathology·View original on PubMed

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Original publication title: Complex mammary adenoma with sebaceous differentiation in a dog.

Species:
dog

Plain-English summary

A 9-year-old miniature pinscher was diagnosed with a complex tumor in her left fourth mammary gland, which had some unusual features including sebaceous (oil-producing) cells. The tumor was made up of different types of cells and structures, which were identified through microscopic examination. While the abstract does not mention treatment or outcome, tumors like this may require surgical removal, and it's important for pet owners to consult their veterinarian for the best course of action.

People also search for: dog mammary tumor treatment · miniature pinscher lump on breast · sebaceous tumor in dogs

Abstract

Sebaceous metaplasia arising within a complex adenoma of the left fourth mammary gland is described in a 9-year-old miniature pinscher bitch. Microscopically, the tumour was composed of tubular and ductular structures admixed with clusters of spindle-shaped, myoepithelial-like cells and units formed of well-differentiated sebocytes surrounded by basaloid cells. Abundant lipid droplets were identified within the latter population by Sudan III staining. Immunohistochemical expression of cytokeratin AE1/AE3 was detected in epithelial cells and in the cells with sebaceous differentiation.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21820669/