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Peer-reviewed veterinary case report

Complex mammary adenoma with sebaceous differentiation in a dog.

Journal:
Journal of comparative pathology
Year:
2012
Authors:
Kurilj, A G et al.
Affiliation:
Department of Veterinary Pathology
Species:
dog

Abstract

Sebaceous metaplasia arising within a complex adenoma of the left fourth mammary gland is described in a 9-year-old miniature pinscher bitch. Microscopically, the tumour was composed of tubular and ductular structures admixed with clusters of spindle-shaped, myoepithelial-like cells and units formed of well-differentiated sebocytes surrounded by basaloid cells. Abundant lipid droplets were identified within the latter population by Sudan III staining. Immunohistochemical expression of cytokeratin AE1/AE3 was detected in epithelial cells and in the cells with sebaceous differentiation.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21820669/