Peer-reviewed veterinary case report
Dog with black raised skin lumps diagnosed with intravascular lymphoma
By VanGessel, Y.A. et al.·Published in Veterinary Dermatology·2000·View original on Crossref →
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Original publication title: Cutaneous presentation of canine intravascular lymphoma (malignant angioendotheliomatosis)
- Species:
- dog
Plain-English summary
A 9-year-old female spayed Boxer was brought to the vet with firm, black, raised lumps on her head, neck, and trunk that often ulcerated and changed in size. After a skin biopsy, the vet diagnosed her with intravascular lymphoma, a type of cancer affecting blood vessels. Unfortunately, despite the diagnosis, the dog passed away four months later, and a post-mortem exam showed cancerous cells in the blood vessels of her brain. This case highlights a rare skin presentation of this aggressive cancer in dogs.
People also search for: Boxer dog skin lumps · dog cancer symptoms · intravascular lymphoma in dogs · raised black masses on dog skin · dog skin cancer treatment
Abstract
A 9‐year‐old female spayed Boxer dog presented with variably sized, firm, black, raised, exudative subcutaneous masses on her head, neck and trunk, that tended to fluctuate in size and frequently ulcerate. Skin biopsy showed that the dermis was expanded by a densely cellular mass of proliferative capillaries distended with large pleomorphic neoplastic round cells mixed with fibrin and erythrocytes. Intravascular lymphoma was diagnosed and immunostains were compatible with a CD8+T lymphocyte histogenesis (CD3+/CD79a−/TCRαβ+/CD8α+). Post‐mortem examination, four months after diagnosis, revealed neoplastic T‐cells within meningeal arteries. We are unaware of other reports of a cutaneous presentation and ante‐mortem diagnosis of intravascular lymphoma in the dog. Additionally, this vasoproliferative form of intravascular lymphoma has not been previously described in dogs.
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Search related cases →Original publication on Crossref: https://doi.org/10.1046/j.1365-3164.2000.00188.x