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Peer-reviewed veterinary case report

Chromosome changes in mammary tumor of 8-year-old German Shepherd dog

By Mayr, B et al.·Published in The British veterinary journal·1991·Institute for Animal Breeding and Genetics·View original on PubMed

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Original publication title: Cytogenetic analysis of a canine haemangioendothelioma: a case report.

Species:
dog

Plain-English summary

An 8-year-old female German Shepherd was diagnosed with a type of tumor called haemangioendothelioma in her mammary area. This tumor was found to have unusual chromosome changes, which can indicate how aggressive the cancer might be. While the study focused on the genetic details of the tumor, it's important for pet owners to know that tumors like this can be serious and may require treatment options such as surgery or chemotherapy. If your dog has a lump or growth, it's best to consult your veterinarian for an evaluation.

People also search for: German Shepherd tumor treatment · dog mammary tumor symptoms · canine cancer chromosome analysis

Abstract

An 8-year-old German Shepherd bitch developed a haemangioendothelioma in the mammary region. The cytogenetic characterization of the tumour cells revealed a chromosome number of 80 plus a double minute. Several aberrations were detected: trisomies 4, 35, and 38, a centric fusion 8/22 and a tandem translocation 9/23.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1777797/