Peer-reviewed veterinary case report
Dog with high calcium and multiple endocrine tumors diagnosis
By Wright, K N et al.·Published in Journal of the American Animal Hospital Association·1995·Department of Companion Animal and Special Species Medicine, United States·View original on PubMed →
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Original publication title: Diagnostic and therapeutic considerations in a hypercalcemic dog with multiple endocrine neoplasia.
- Species:
- dog
Plain-English summary
A dog was brought in for weakness and confusion, and tests revealed high calcium levels in the blood. An ultrasound showed a mass on the right adrenal gland, which was identified as a pheochromocytoma, a type of tumor. After surgery to remove the tumor, the dog's calcium levels returned to normal for a while, but later tests indicated another issue with the parathyroid glands, suggesting a tumor there as well. The dog will need further evaluation and treatment for the suspected parathyroid tumor.
People also search for: dog weakness and confusion · high calcium levels in dogs · pheochromocytoma treatment in dogs · parathyroid tumor in dogs
Abstract
Hypercalcemia was found in a dog examined for episodic weakness and disorientation. A right adrenal mass identified on abdominal ultrasonographic examination was diagnosed as a pheochromocytoma based on increased 1231-metaiodobenzylguanidine uptake and characteristic histopathological features. Serum intact parathyroid hormone (iPTH), total serum calcium, and ionized serum calcium were increased prior to surgery. Although both total and ionized serum calcium concentrations decreased to within normal reference ranges following surgery through postoperative day 17, subsequent high concentrations with increased serum iPTH concentrations confirmed concurrent primary hyperparathyroidism. A right parathyroid tumor was suspected based on a technetium-99m-sestamibi (99mTc-sestamibi) scan.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7773762/