Peer-reviewed veterinary case report
Serum glycated albumin helps diagnose diabetes in dogs
By Sako, Toshinori et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2008·Department of Veterinary Science, Japan·View original on PubMed →
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Original publication title: Diagnostic significance of serum glycated albumin in diabetic dogs.
- Species:
- dog
Plain-English summary
A study found that measuring glycated albumin (GA) in diabetic dogs can help veterinarians monitor their blood sugar levels. This is important because traditional tests like fructosamine aren't commonly used in some places, like Japan. The researchers discovered that higher levels of GA were linked to poorer blood sugar control in dogs. This means that GA could be a good alternative test for tracking diabetes management in dogs. Overall, this could help pet owners and vets better manage their diabetic dogs' health.
People also search for: diabetic dog treatment · how to manage dog diabetes · glycated albumin test for dogs
Abstract
Measurements of serum fructosamine, glycated hemoglobin, and glycated albumin (GA) are increasingly used to complement serum glucose concentration for better management of diabetes mellitus. Fructosamine tests are currently not performed in veterinary medicine in Japan. As such, the measurement of GA may serve as a replacement test. Therefore, in the current study, serum GA and fructosamine were evaluated for a positive correlation in dogs, and, depending on the correlation, a reference range of GA percentage would also be determined from healthy control dogs. The degree of glycemic control in diabetic dogs was determined by fructosamine concentration. A positive correlation between GA and fructosamine was observed with both normal and diabetic animals. In addition, the reference interval of serum GA percentage in control dogs was determined to be 11.4-11.9% (95% confidence interval). Interestingly, no significant difference in serum GA percentages was observed between samples from diabetic dogs with excellent glycemic control and control dogs. However, good, fair, and poor glycemic control diabetic dogs resulted in a significant increase in serum GA percentages in comparison with control dogs. These results suggest that serum GA may be a useful diagnostic indicator, substituting for fructosamine, to monitor glycemic control in diabetic dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18776099/