Peer-reviewed veterinary case report
Young miniature dachshund with thickened gut wall from diffuse
By Kuramochi, Mizuki et al.·Published in The Journal of veterinary medical science·2020·Osaka Prefecture University, Japan·View original on PubMed →
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Original publication title: Diffuse leiomyomatosis with circumferential thickening of the gastrointestinal wall, resembling human diffuse leiomyomatosis, in a young miniature dachshund.
- Species:
- dog
Plain-English summary
A 3-year-old female miniature dachshund sadly passed away after experiencing severe rectal prolapse and breathing problems due to aspiration pneumonia. During the examination after her death, veterinarians found that her gastrointestinal wall was thickened in certain areas, which is unusual for dogs. The thickening was caused by a type of tumor called diffuse leiomyomatosis, which is made up of smooth muscle cells but does not form a mass or invade surrounding tissues. Unfortunately, there were no effective treatments for this rare condition, and it ultimately led to her death.
People also search for: dog rectal prolapse treatment · miniature dachshund breathing problems · dog gastrointestinal tumors symptoms
Abstract
Leiomyoma is the most common mesenchymal tumor in the gastrointestinal (GI) tract. Leiomyomas usually have a single or multinodular mass of various sizes, and affected animals can develop alimentary symptoms depending on the location and size. A 3-year old female miniature dachshund died after a history of refractory rectal prolapse, esophagectasis and aspiration pneumonia. At necropsy, the GI wall at the gastroesophageal and anorectal junctions was circumferentially thickened. Histologically, both GI lesions were composed of bundles of well-differentiated smooth muscles without mass formation or invasive growth. The neoplastic cells had little cellular atypia and low proliferative activity, and were positive for α-smooth muscle actin. The lesions were diagnosed as diffuse leiomyomatosis with circumferential thickening of the GI wall and has not been described in the veterinary literature.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31852861/