Peer-reviewed veterinary case report
Glucosamine-chondroitin does not change blood sugar marker in healthy
By Lenox, Catherine E & Lunn, Katharine F·Published in Journal of the American Veterinary Medical Association·2010·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Effects of glucosamine-chondroitin sulfate supplementation on serum fructosamine concentration in healthy dogs.
- Species:
- dog
Plain-English summary
A group of 12 healthy adult dogs was given a glucosamine-chondroitin sulfate (Glu-CS) supplement to see if it would change their blood sugar levels, as measured by serum fructosamine concentration. After three weeks of taking the supplement and a placebo, the results showed no significant differences in blood sugar levels between the two treatments. This means that short-term use of Glu-CS does not appear to affect blood sugar control or lead to diabetes in healthy dogs.
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Abstract
OBJECTIVE: To determine whether short-term administration of an oral glucosamine-chondroitin sulfate (Glu-CS) supplement alters serum fructosamine concentration in healthy dogs. DESIGN: Prospective crossover study. ANIMALS: 12 healthy adult dogs. PROCEDURES: Dogs received Glu-CS and a placebo for 3 weeks each, with a 4-week minimum washout period between treatments. Serum fructosamine concentration was measured 4 times for each dog: prior to the first treatment period, at the end of the first treatment period, at the end of the washout period, and at the end of the second treatment period. RESULTS: No significant change in serum fructosamine concentration was identified after treatment with either Glu-CS or the placebo. The change in serum fructosamine concentration associated with Glu-CS administration was not significantly different from the change in concentration associated with administration of the placebo. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that in healthy dogs, short-term (ie, 21 days) oral Glu-CS administration does not affect glycemic control or cause diabetes mellitus.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20074008/