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Peer-reviewed veterinary case report

Efficacy of benzoxazinorifamycins in a mouse model of Chlamydia pneumoniae lung infection.

Journal:
Antimicrobial agents and chemotherapy
Year:
2008
Authors:
Campbell, Lee Ann et al.
Affiliation:
Department of Pathobiology · United States

Abstract

The efficacy of rifalazil and other benzoxazinorifamycins was tested in a mouse model of lung infection against Chlamydia pneumoniae. Rifalazil and six related new chemical entities all showed efficacy after one dose per day for 3 days at either 3 or 1 mg/kg of body weight.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18332169/