Peer-reviewed veterinary case report
Rifalazil and derivative compounds show potent efficacy in a mouse model of H. pylori colonization.
- Journal:
- The Journal of antibiotics
- Year:
- 2008
- Authors:
- Rothstein, David M et al.
- Affiliation:
- ActivBiotics · United States
Abstract
The rifamycin rifalazil (RFZ), and derivatives (NCEs) were efficacious in a mouse model of Helicobacter pylori colonization. Select NCEs were more active in vitro and showed greater efficacy than RFZ. A systemic component contributes to efficacy.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18997386/