Peer-reviewed veterinary case report
High heart troponin in dog with brain tumor and heart damage
By Kent, Marc et al.·Published in Journal of the American Animal Hospital Association·2010·Department of Small Animal Medicine and Surgery, United States·View original on PubMed →
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Original publication title: Elevated cardiac troponin I in a dog with an intracranial meningioma and evidence of myocardial necrosis.
- Species:
- dog
Plain-English summary
A 10-year-old spayed female Weimaraner was brought in for sudden shaking, seizures, and confusion. The vet found that she had a serious brain issue, specifically a tumor in the left olfactory bulb, which was causing swelling in her brain. Blood tests showed high levels of cardiac troponin I, indicating damage to her heart muscle. Unfortunately, the dog passed away, and further examination confirmed both the brain tumor and heart damage. This case highlights the connection between brain tumors and heart problems in dogs.
People also search for: dog seizures and shaking · Weimaraner heart problems · elevated cardiac troponin in dogs · brain tumor in dogs symptoms · dog neurological issues
Abstract
A 10-year-old, spayed female Weimaraner was referred for an acute onset of generalized tremors, seizures, and obtundation. Neurological examination revealed severe obtundation and a right-sided menace response deficit. Neuroanatomical diagnosis was consistent with a left prosencephalic lesion. The serum cardiac troponin I level was high, indicative of acute myocardial necrosis. With magnetic resonance imaging, a mass was observed in the left olfactory bulb and tract, with extensive edema in the white matter of the left cerebrum. The hippocampus was hyperintense on T2-weighted and T2-weighted fluid-attenuated inversion recovery images. At necropsy, a meningioma of the left olfactory bulb and ischemic cell change in the neurons of the hippocampus were identified. In the heart, microscopic lesions consistent with myocardial necrosis were observed. This is the first case to document an elevated cardiac troponin I level in a dog with intracranial disease and myocardial necrosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20045837/