Peer-reviewed veterinary case report
Mammary tumors in female dogs in Japan's Kyushu-Okinawa region
By Hirano, Shinji et al.·Published in Veterinary journal (London, England : 1997)·2025·Joint Faculty of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Epidemiological analysis of mammary tumors in female dogs in Japan: A study based on Kyushu-Okinawa region.
- Species:
- dog
Plain-English summary
A study in Japan found that mammary tumors are common in female dogs, with nearly half being malignant. The research looked at over 7,800 cases from 2005 to 2023 and found that older dogs, especially those aged 8 and up, are at higher risk. Neutered female dogs had a lower chance of developing these tumors compared to those that were not neutered. This information can help pet owners understand the risks and encourage discussions with their veterinarians about preventive measures and early detection.
People also search for: female dog mammary tumors · dog cancer risk factors · neutering benefits for dogs · older dog health issues · mammary tumor treatment in dogs
Abstract
Canine mammary tumors (CMTs) are common tumors in female dogs (FDs), and at least nearly half of these lesions of malignant. We examined the epidemiology of CMTs in Japan using excisional biopsy cases (n = 7802) collected from 2005 to 2023 in the Kyushu-Okinawa region. We investigated the prevalence, effects of breed, neutering, and age on CMT and malignant CMT (mCMT) risk through general statistics and multivariate analyses. The distribution of CMT histological types was also compared among different breeds and mixed breeds. In the Cohort (n = 6197) consisting of cases from primary veterinary hospitals, the numbers of CMT and mCMT cases (2928 and 822 cases, respectively) and the adjusted prevalence is ranged 4.76-8.09 per 1000 dogs and increasing over time (P < 0.001). A multivariate model identified breeds with high or low risks of CMT or mCMT. Neutered FDs had lower risk of CMT than intact FDs (risk ratio = 0.57, 95 %CI: 0.53-0.61). Compared to the age with the highest incidence, those aged ≥ 8 and ≥ 14 years had comparable rates of CMT and mCMT, respectively. Certain breeds exhibited biases regarding CMT histological types compared to mixed breeds. This first epidemiological analysis of CMT in Japan will be a valuable resource for CMT control.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39818359/