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Peer-reviewed veterinary case report

Cutaneous histiocytoma in young dogs by breed and location

By C. D. de Moura et al.·Published in Veterinary dermatology (Print)·2026·View original on Semantic Scholar

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Original publication title: Epidemiology of Canine Cutaneous Histiocytoma: Insights From Age and Topographic Clustering

Species:
dog

Plain-English summary

A study found that canine cutaneous histiocytoma (CCH), a benign skin tumor, is most common in young male dogs, particularly French bulldogs and Boxers. These tumors often appear in dogs under two years old and can regress on their own due to inflammation. The research showed that the incidence of CCH is higher in specific breeds and locations, which can help veterinarians identify and monitor at-risk dogs. If your dog develops a lump on the skin, it's important to have it checked by a vet, but many cases resolve without treatment.

People also search for: dog skin lump French bulldog · Boxer skin tumor treatment · why is my dog developing lumps

Abstract

Canine cutaneous histiocytoma (CCH) is a benign Langerhans‐cell tumour that often regresses spontaneously via inflammation. To estimate incidence and characterise age and breed–anatomical‐site patterns using two complementary clustering analyses. A total of 359 histopathologically‐confirmed CCHs from a private veterinary laboratory in Portugal (January 2020–January 2022) were analysed with dog‐population denominators from the national registry (SIAC). Incidence rates (IR) were calculated for Lisbon–Setúbal; breed‐ and sex‐specific relative risks (RR) were estimated. Age was modelled with BIC‐selected Gaussian mixtures; breed–site patterns were summarised by hierarchical clustering of site frequencies (heatmaps). Cases concentrated in young dogs (≤ 2 years, 48.8%) and males (58.5%). Age clustering defined three bands (≈ ≤ 1.5, 1.5–3.5, > 3.5 years) with differing breed and site distributions. Breed–site clustering revealed recurring anatomical predilections by breed and sex. The annual IR in Lisbon–Setúbal was 4.0 per 10,000 dogs (3.5 in females; 4.4 in males). Risk was highest in French bulldogs (RR 11.5; IR 34.1) and Boxers (RR 8.3; IR 24.5) versus mixed‐breed dogs ( p  < 0.001). Canine cutaneous histiocytoma (CCH) shows clear age bands and breed‐linked anatomical predilections; these patterns help prioritise ages, sites and breeds for studies of inflammation‐mediated regression.

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Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/abcd5da7592d09f1263d89eb8d79cf1166978a52