Peer-reviewed veterinary case report
Preputial cytology helps diagnose estrogen testicular tumors in dogs
By Dreimanis, U et al.·Published in The Journal of small animal practice·2012·Department of Small Animals·View original on PubMed →
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Original publication title: Evaluation of preputial cytology in diagnosing oestrogen producing testicular tumours in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with testicular masses was evaluated for signs of hormonal issues, such as hair loss and feminization. Researchers found that a specific type of cell in a preputial smear (a sample taken from the penis) was linked to higher levels of estrogen, which can indicate the presence of estrogen-producing testicular tumors. The study suggests that this test could be a reliable way for veterinarians to diagnose these tumors in dogs. Neutering the affected dogs and examining the testicular tissue confirmed the diagnosis.
People also search for: dog testicular tumor symptoms · dog hair loss estrogen · diagnosing testicular tumors in dogs
Abstract
OBJECTIVES: The purpose of this study was to evaluate the diagnostic sensitivity and specificity of preputial cytology in oestrogen producing testicular tumours in dogs. METHODS: Forty-five dogs with palpable testicular masses and 30 healthy control dogs were included. Dogs were evaluated for signs of alopecia and/or feminisation. Analyses of preputial cytology, haematology and serum oestradiol were performed. Dogs with testicular masses were neutered and the testes were submitted for histopathological examination. The dogs were divided into three groups (1) control dogs (n=30), (2) dogs with a testicular mass and serum oestradiol concentration <40 pmol/L (n=35), (3) dogs with a testicular mass and serum oestradiol concentration >40 pmol/L (n=10). RESULTS: More than 20% superficial cells in preputial smear was significantly associated with serum oestradiol concentration >40 pmol/L (P<0·001). The number of superficial cells was significantly increased (P<0·001) in preputial smears from dogs with alopecia. CLINICAL SIGNIFICANCE: It appears that the preputial cytology has a high sensitivity and specificity for the diagnosis of oestrogen producing testicular tumours in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22861159/