Peer-reviewed veterinary case report
Heart injury and arrhythmias found in dogs with acute kidney injury
By Keller, S P et al.·Published in The Journal of small animal practice·2016·Department of Clinical Veterinary Medicine·View original on PubMed →
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Original publication title: Evidence of cardiac injury and arrhythmias in dogs with acute kidney injury.
- Species:
- dog
Plain-English summary
A group of 24 dogs with acute kidney injury, most of which had leptospirosis, were evaluated for heart problems. Some of these dogs showed signs of cardiac injury, including abnormal heart rhythms, which were monitored using various tests. The study found that dogs with more than 100 abnormal heartbeats in a day had higher levels of a specific heart injury marker. While the heart issues did not directly cause poor outcomes, they were linked to the severity of the kidney disease. Treatment focused on managing the kidney injury, and monitoring heart health was crucial for these dogs.
People also search for: dog acute kidney injury treatment · dog heart problems with kidney disease · leptospirosis in dogs symptoms
Abstract
OBJECTIVES: Cardiac involvement in the course of acute kidney injury is described in humans as cardiorenal syndrome type 3 but has received only limited attention in dogs. This study was designed to evaluate cardiac injury and dysfunction in acute kidney injury in dogs and its association with outcome. METHODS: This prospective cohort study enrolled 24 client-owned dogs with acute kidney injury. Cardiac disorders were evaluated with thoracic radiographs, echocardiography, 24-hour Holter monitoring and cardiac troponin I concentrations within 2 days of admission and 7 to 10 days later. RESULTS: Most dogs were diagnosed with leptospirosis (n=18, 75%) and presented with moderate-to-severe acute kidney injury, International Renal Interest Society grades III to V. Dogs with ê100 ventricular premature complexes per 24 hour in the first examination (n=8) had significantly higher initial cTnI concentrations (P=0·007) compared to dogs with fewer than 100. In receiver operating characteristic curve analysis, the number of ventricular premature complexes was predictive of outcome (AUC 0·83, P<0·001). CLINICAL SIGNIFICANCE: Acute kidney injury seems to be associated with cardiac injury and arrhythmias in dogs. The data do not indicate a cardiac cause of poor outcome in dogs with increased number of ventricular premature complexes but the association may reflect the severity of disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27357259/