Peer-reviewed veterinary case report
Survival after Co-60 radiotherapy for dog nasal tumors by treatment
By Yoon, J H et al.·Published in Research in veterinary science·2008·College of Veterinary Medicine and BK21 Program for Veterinary Science, South Korea·View original on PubMed →
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Original publication title: External-beam Co-60 radiotherapy for canine nasal tumors: a comparison of survival by treatment protocol.
- Species:
- dog
Plain-English summary
A group of dogs with nasal tumors were treated with different types of radiation therapy to see which helped them live longer. The study looked at 139 dogs and found that those receiving three or more radiation treatments per week, with a total dose of at least 37 Gy, had better survival rates. However, other factors like the type of tumor or the number of treatments did not significantly affect how long the dogs lived. This suggests that a more intensive radiation schedule may be beneficial for dogs with nasal tumors.
People also search for: dog nasal tumor treatment · canine radiation therapy survival · dog cancer treatment options
Abstract
A retrospective analysis of survival times in dogs with intranasal tumors was performed comparing those treated using hypofractionated or full course Co-60 radiotherapy protocols alone or with surgical adjuvant therapy and those receiving no radiation treatment. One hundred thirty-nine dogs presented to the University of Minnesota Veterinary Medical Center for treatment of histologically-confirmed nasal neoplasia between July 1983 and October 2001 met the criteria for review. Statistically analyzed parameters included age at diagnosis, tumor histologic classification, fractionation schedule (number of treatments, and number of treatment days/week) (classified as hypofractionated if 2 or less treatments/week); calculated minimum tumor dose/fraction; calculated total minimum tumor dose (classified as hypofractionated if less than 37 Gy in six or fewer fractions); number of radiotherapy portals, a treatment gap of more than 7 days in a full course (3-5 treatments/week, 3-3.5 week treatment time) radiotherapy protocol, the influence of eye shields on survival following single portal DV fields, the survey radiographic extent of the disease, and the presence or absence of cytoreductive surgery. There was a significant relationship only between protocols using 3 or more treatments/week and at least 37 Gy cumulative minimum tumor dose and survival. However, there was no significant relationship between either total minimum tumor dose or dose/fraction and survival and there were no significant relationships between survival and any of the other variables analyzed including tumor histologic type.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17950765/