Peer-reviewed veterinary case report
Food allergens inducing a lymphocyte-mediated immunological reaction in canine atopic-like dermatitis.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2015
- Authors:
- Suto, Akemi et al.
- Affiliation:
- Suto Animal Hospital · Japan
- Species:
- dog
Plain-English summary
In this study, researchers looked at 54 dogs with a skin condition called canine atopic-like dermatitis (ALD), which is thought to be linked to food allergies. They found that 90.7% of these dogs had immune reactions to certain food allergens, particularly soybean, which affected 21 dogs. The least common allergen was catfish, with only 5 dogs reacting to it. These findings suggest that identifying specific food allergens could help in creating elimination diets to manage the symptoms of ALD in dogs. Overall, the study indicates that food allergies may play a significant role in this skin condition.
Abstract
Canine atopic-like dermatitis (ALD) is suspected to be associated with food allergies, particularly those mediated by lymphocytes. In this study, 54 cases were included as ALD dogs, based on the negative IgE test results. In the dogs, the percentage of activated cells in helper-T lymphocytes was measured by flow cytometry using cultured peripheral lymphocytes under food allergen stimulation. We observed that 49 of the 54 ALD dogs (90.7%) had positive lymphocyte reactions against one or more food allergens. The most common food allergen was soybean, showing positive results in 21 dogs (42.9%), while the allergen to cause the lowest number of reactions was catfish (only 5 dogs, 10.2%). These results may be useful in considering elimination diets for ALD dogs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25728252/