Peer-reviewed veterinary case report
High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals.
- Journal:
- Journal of veterinary science
- Year:
- 2020
- Authors:
- Sum, Samuth et al.
- Affiliation:
- Department of Veterinary Internal Medicine · South Korea
Abstract
The purpose of this study was to investigate the high-level mupirocin resistance (HLMR) in Gram-positive bacteria isolated from companion animals. A total of 931 clinical specimens were collected from diseased pets. The detection of mupirocin-resistant bacteria and plasmid-mediated mupirocin resistance genes were evaluated by antimicrobial susceptibility tests, polymerase chain reactions, and sequencing analysis. Four-hundred and six (43.6%) bacteria were isolated and 17 (4.2%), including 14 staphylococci and 3were high-level mupirocin-resistant (MICs, ≥ 1,024 ug/mL) harboring. Six staphylococci of HLMR strains had plasmid-mediated-ISflanking regions. The results show that HLMR bacteria could spread in veterinary medicine in the near future.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/32476314/