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Peer-reviewed veterinary case report

Histiocytic sarcoma of the nasal cavity in a horse.

Journal:
Research in veterinary science
Year:
2013
Authors:
Paciello, O et al.
Affiliation:
Department of Pathology and Animal Health · Italy
Species:
horse

Plain-English summary

A 9-year-old female Dutch Warmblood horse was brought to the vet because she had severe bleeding from her nose. During the examination, the vet found a large, irregular mass about 5 cm wide that was reddish to white and had damaged nearby tissues. The cells from this mass looked unusual and had multiple nuclei, which helped the vet identify it as a histiocytic sarcoma, a type of tumor. This condition is considered rare in horses, but the findings confirmed the diagnosis.

Abstract

Histiocytic diseases in veterinary medicine have been revised in the last few decades, but these are considered relatively rare in horses. This report describes a 9-year-old female horse, Dutch Warmblood, presented for investigation of severe nasal bleeding. A multinodular bilateral mass of 5 cm, reddish to white in color, that invaded and destroyed the surrounding tissues, was observed during a clinical examination of the nostril The morphological features of the tumor cells were represented by cytologically bizarre, highly phagocytic, multinucleated giant cells. These findings, together with immunohistochemical results allowed a diagnosis of histiocytic sarcoma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23395306/