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Peer-reviewed veterinary case report

Venom allergy shots for a young Beagle without human serum albumin

By Apostolopoulos, Neoklis & Mayer, Ursula·Published in Veterinary Record Case Reports·2021·Dermatology AniCura Kleitierspezialisten Augsburg GmbH Augsburg Germany, Germany·View original on Crossref

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Original publication title: Hymenoptera venom immunotherapy without human serum albumin as a stabilizer in a canine patient

Species:
dog

Plain-English summary

A 4-month-old female Beagle with a history of severe allergic reactions to bee stings was treated with venom immunotherapy (VIT) to help her build tolerance. Instead of using a common stabilizer that could cause more allergic reactions, the vet used water as a safer alternative. After 11 months of treatment, the dog was stung by a bee but only experienced mild swelling of her lips, showing that the therapy was effective. She has continued the treatment for over 35 months without any serious issues.

People also search for: dog bee sting allergy treatment · Beagle anaphylactic reaction · venom immunotherapy for dogs

Abstract

Abstract A four‐month‐old female Beagle, with a history of repeated anaphylactic reactions, was managed with venom immunotherapy (VIT), based on the results of a blood allergy test. Because there is a lack of VIT for dogs, a product from human medicine was used, which requires human serum albumin (HSA) in the solvent as a stabilizer. HSA has been described to cause sensitization and anaphylactic reactions, as well as other adverse effects in dogs. To avoid such adverse effects, water for injection was used as a solvent. VIT was initiated with a one‐day ultra‐rush induction scheme, followed by a conventional protocol as maintenance. The dog was stung by a bee after 11 months of VIT, presenting only mild lip edema. VIT is performed for the last 35 months. To the authors’ knowledge, this is the first report of a successful VIT using water for injection as a solvent, without HSA.

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Original publication on Crossref: https://doi.org/10.1002/vrc2.13