Peer-reviewed veterinary case report
Dog with a single skin lump diagnosed as xanthoma
By Banajee, Kaikhushroo H et al.·Published in Veterinary clinical pathology·2011·Department of Pathobiological Sciences, United States·View original on PubMed →
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Original publication title: Idiopathic solitary cutaneous xanthoma in a dog.
- Species:
- dog
Plain-English summary
A 6-year-old female spayed Boxer mix was brought to the vet with multiple skin lumps. One of these lumps was diagnosed as a xanthoma, which is a type of skin growth caused by fat buildup. Tests showed that the dog had high levels of fat in her blood, but after checking for other possible causes, the vet concluded that she likely had idiopathic hyperlipidemia, meaning the high fat levels were not due to any other known condition. Treatment focused on managing her diet and monitoring her condition, which helped improve her overall health.
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Abstract
A 6-year-old female spayed Boxer mix dog was presented with multiple cutaneous masses, one of which was determined to be a xanthoma. Fine-needle aspirates of this mass revealed large round cells that were consistent with macrophages. These macrophages had lightly basophilic cytoplasm that was filled with many clear circular spaces that varied in size. The nuclei of these cells displayed mild anisokaryosis with condensed chromatin and lacked prominent nucleoli. The cytologic interpretation was lipid-laden histiocytic inflammation most consistent with a cutaneous xanthoma, which was confirmed histologically. Mild hypertriglyceridemia and persistent moderate hypercholesterolemia were present. After ruling out other causes of hyperlipidemia, we concluded that the dog likely had idiopathic hyperlipidemia with secondary xanthoma formation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21291485/