Peer-reviewed veterinary case report
Immune-mediated anemia linked to lymphoblastic infiltration in two
By Gunn-Moore, D A et al.·Published in Journal of feline medicine and surgery·1999·Department of Pathology and Microbiology, United Kingdom·View original on PubMed →
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Original publication title: Immune-mediated haemolytic anaemia in two sibling cats associated with multicentric lymphoblastic infiltration.
- Species:
- cat
Plain-English summary
Two sibling cats, both under 16 months old, were brought to the vet showing signs of severe anemia, which means they had low red blood cell counts. Tests revealed that their immune systems were mistakenly attacking their own red blood cells, a condition known as immune-mediated hemolytic anemia. Unfortunately, despite medical intervention, both cats passed away within two months of being diagnosed. Further examination after their deaths showed that their bodies had developed abnormal lymphoblasts, which are immature white blood cells, in their bone marrow, liver, and spleen.
People also search for: cat anemia symptoms · immune-mediated hemolytic anemia in cats · sibling cats with anemia · cat lymphoblastic infiltration treatment
Abstract
Immune-mediated haemolytic anaemia associated with multicentric lymphoblastic infiltration is reported in two sibling cats. Both cats presented at under 16 months of age with clinical signs of acute anaemia. In each case there was autoagglutination, a positive Coombs' test and the anaemia was regenerative. At presentation, both cats were negative for FeLV antigen. In each case, the disease proved fatal within 2 months of the initial diagnosis. In both cases, T-lymphoblastic infiltration of bone marrow, liver and spleen was found at post-mortem examination.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11714237/