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Peer-reviewed veterinary case report

Immune-mediated hemolytic anemia associated with trimethoprim-sulphamethoxazole administration in a horse.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
1998
Authors:
Thomas, H L & Livesey, M A
Affiliation:
Department of Clinical Studies · Canada
Species:
horse

Plain-English summary

A 10-year-old thoroughbred gelding received a type of medication called sulphonamides during surgery for a fungal infection in his throat area. After starting the medication, he developed anemia, which means his blood had fewer red blood cells than normal. The vets determined that the anemia was caused by his immune system mistakenly attacking his own red blood cells, a condition known as immune-mediated hemolytic anemia. Once the medication was stopped, his anemia improved and resolved.

Abstract

A 10-year-old, thoroughbred gelding was administered sulphonamide drugs during surgical treatment of guttural pouch mycosis. The horse became anemic and a diagnosis of immune-mediated hemolytic anemia was made after other causes of anemia had been ruled out. The anemia resolved after the drugs were withdrawn.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/9524723/