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Peer-reviewed veterinary case report

Ovarian tumor diagnosed by immunohistochemistry in a female dog

By Park, J K et al.·Published in Reproduction in domestic animals = Zuchthygiene·2009·Department of Veterinary Pathology, South Korea·View original on PubMed

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Original publication title: Immunohistochemistry diagnosis of an ovarian dysgerminoma in one bitch.

Species:
dog

Plain-English summary

A 5-year-old female dog had an 8 cm enlargement in her ovary that was surgically removed. After examining the tissue under a microscope, the vet found it was a type of tumor called a dysgerminoma, which is a form of ovarian cancer. The tumor showed signs of abnormal cell growth and damage. The dog underwent surgery to remove the tumor, and while the abstract does not specify the outcome, early detection and surgical removal are often key to better prognosis in such cases.

People also search for: dog ovarian tumor treatment · female dog tumor symptoms · what is dysgerminoma in dogs

Abstract

An ovarian enlargement (diameter, 8 cm) was identified and surgically excised from a 5-year-old female dog. Microscopic examination of the multinodular neoplasm revealed sheets of polygonal neoplastic cells with large nuclei, frequent mitosis, necrosis and haemorrhage. Immunohistochemically, the neoplastic cells were positive for vimentin and alkaline phosphatase but were negative for CD3, CD79a, cytokeratin, alpha-fetoprotein, inhibin-alpha and S-100. The histopathological diagnosis of the mass was unilateral ovarian dysgerminoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18992107/