Peer-reviewed veterinary case report
Inflammatory myofibroblastic tumors found in two dogs
By Knight, C et al.·Published in Veterinary pathology·2009·Institute of Veterinary·View original on PubMed →
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Original publication title: Inflammatory myofibroblastic tumors in two dogs.
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog and a 7-year-old Labrador were found to have soft tissue masses that were examined by a veterinarian. These masses were diagnosed as inflammatory myofibroblastic tumors (IMT), which are unusual growths that can occur in dogs. The tumors were well-defined and made up of specific types of cells that indicated their inflammatory nature. While the study does not detail treatment outcomes, early detection and surgical removal are typically recommended for managing such tumors.
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Abstract
Two soft tissue masses from different locations in 2 dogs were submitted for histopathologic examination. Each was well demarcated and consisted of interweaving streams of bland spindle cells among which numerous plasma cells and lymphocytes were scattered. All the spindle cells reacted strongly to antibodies against vimentin and calponin, whereas a subset of the spindle cells expressed smooth muscle actin and desmin. Immunohistochemistry results were consistent with a myofibroblastic derivation for the spindle-cell population and the diagnosis of inflammatory myofibroblastic tumor (IMT) was made. This is the second report of IMT in the veterinary literature.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19261639/