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Peer-reviewed veterinary case report

Dog with nasal tumor causing sneezing and nosebleeds

By Swinbourne, F et al.·Published in The Journal of small animal practice·2014·Department of Veterinary Clinical Sciences·View original on PubMed

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Original publication title: Inflammatory myofibroblastic tumour in the nasal cavity of a dog.

Species:
dog

Plain-English summary

A 4.5-year-old female neutered Leonberger was brought to the vet with sneezing, nasal discharge, and nosebleeds that had been going on for two months. Initially, the vet thought it might be a fungal infection in the nose, but treatment didn’t help, and further scans revealed a growing mass. After surgery to remove the mass, the dog showed significant improvement, with no more nasal discharge and less sneezing reported nine months later. This case highlights that an inflammatory myofibroblastic tumor can occur in a dog's nasal cavity, especially when symptoms don't match typical infections.

People also search for: dog sneezing and nasal discharge · Leonberger nasal tumor treatment · dog nosebleed causes

Abstract

A 4·5-year-old, female neutered Leonberger was presented with a 2-month history of sneezing, nasal discharge and epistaxis. A presumptive diagnosis of nasal aspergillosis was made based on a suspected (fungal) granuloma on rhinoscopic examination and fungal hyphae on cytological examination. A poor response to targeted therapy was observed and computed tomography 16 months after initial presentation revealed a progressive, locally invasive mass lesion. Histopathological and immunohistochemical analysis of deep surgical biopsies revealed a spindle cell population and a plasma cell rich inflammatory infiltrate, with diffuse expression of vimentin, supporting a diagnosis of inflammatory myofibroblastic tumour. Complete resolution of the nasal discharge and reduced sneezing frequency was reported 9 months post-surgical debridement via rhinotomy. To the authors' knowledge, this is the first report of IMT in the nasal cavity of a dog. IMT should be considered when presented with a nasal mass lesion, particularly if histopathological features and clinical course are inconsistent.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24117751/