Peer-reviewed veterinary case report
Fish oil diet effects on blood sugar and weight in overweight dogs
By de Godoy, M R C et al.·Published in Journal of animal physiology and animal nutrition·2018·Department of Animal and Food Sciences, United States·View original on PubMed →
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Original publication title: Influence of feeding a fish oil-containing diet to mature, overweight dogs: Effects on lipid metabolites, postprandial glycaemia and body weight.
- Species:
- dog
Plain-English summary
Seven overweight female dogs were fed either a regular diet or a diet containing fish oil to see how it affected their weight and cholesterol levels. The study found that the fish oil diet significantly lowered cholesterol levels after 30, 60, and 69 days, but it didn't change their body weight or food intake. While there were some changes in glucose metabolism, more research is needed to fully understand the effects of fish oil on blood sugar levels. Overall, adding fish oil to the diet may help reduce cholesterol in overweight dogs.
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Abstract
The objective of this study was to determine the effect of feeding a fish oil (FO)-containing diet on lipid and protein metabolism, postprandial glycaemia and body weight (BW) of mature, overweight dogs. Seven female dogs were randomly assigned to one of two isonitrogenous and isocaloric diets, control (CO) or FO (FO), in a crossover design. Experimental periods were 69 day, separated by a washout period of 30 day. At the beginning of the experiment, and at 30 and 60 day of feeding the experimental diets, the dogs were infused with D-glucose (2 g/kg BW) through an intravenous catheter. Blood samples were collected for 3 hr to perform a glucose tolerance test. Nitrogen balance measurements began at 06:30 on d 63 of each experimental period and ended at 06:30 on d 69. On d 66 of each period, a single dose (7.5 mg/kg) ofN-glycine was administered orally for determination of protein turnover. Incremental area under the curve and glucose concentration at peak did not differ between treatments or among sampling days within treatment. Glucose half-life tended to decrease (p < .10) in the FO treatment on day 30 when compared to baseline (day 0). β-hydroxybutyrate, non-esterified fatty acid (NEFA) and triglycerides did not differ within or between treatments. Cholesterol decreased (p < .05) on the FO treatment on day 30, 60 and 69 when compared to day 0. High-density lipoprotein (HDL) decreased (p < .05) in the FO treatment on day 69 when compared to day 0. Body weight, food intake, faecal excretion, DM and N digestibilities, N balance and protein turnover were not different between diets. Overall, FO-containing diet decreases cholesterol in mature overweight dogs; however, further research is warranted to verify the effects of FO on glucose metabolism.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28503817/