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Peer-reviewed veterinary case report

Inhibitory effect of antiserum to surface antigen P50 of Babesia gibsoni on growth of parasites in severe combined immunodeficiency mice given canine red blood cells.

Journal:
Infection and immunity
Year:
2004
Authors:
Fukumoto, Shinya et al.
Affiliation:
Obihiro University of Agriculture and Veterinary Medicine · Japan

Abstract

The inhibitory effect of an antiserum to surface protein P50 of Babesia gibsoni on the growth of the parasite was determined with severe combined immunodeficiency mice given canine red blood cells. The antiserum to the recombinant P50 protein significantly inhibited the parasite growth, indicating that P50 might be a useful vaccine candidate.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/14977989/