Peer-reviewed veterinary case report
Dog with gall bladder tumor causing high blood pressure during surgery
By Horikirizono, H et al.·Published in The Journal of small animal practice·2024·Joint Faculty of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Intraoperative hypertensive crisis in a dog with functional paraganglioma of the gall bladder.
- Species:
- dog
Plain-English summary
A 15-year-old spayed female mongrel was brought to the vet because she wasn't eating and had an abdominal mass. During surgery to remove the mass from her gall bladder, the dog experienced high blood pressure and a fast heart rate, but these issues improved significantly after the mass was removed. The mass was identified as a functional paraganglioma, a type of tumor that can affect hormone levels. After surgery, her hormone levels returned to normal, and follow-up exams showed no signs of cancer returning for over a year.
People also search for: dog abdominal mass · dog gall bladder tumor · dog not eating treatment · functional paraganglioma in dogs
Abstract
A 15-year-old spayed female mongrel presented with anorexia and an abdominal mass. The mass originated from the gall bladder and was surgically resected along with divisionectomy of the central hepatic division. Paroxysmal hypertension and tachycardia were noted during manipulation of the mass. Following resection, arterial blood pressure decreased significantly. Histopathological analysis confirmed a diagnosis of neuroendocrine neoplasm. Immunohistochemical staining for synaptophysin and chromogranin A yielded diffuse and strong positive results, while gastrin was positive in only 10% of the cells. The preoperative elevated concentrations of catecholamine in the urinalysis showed a marked decrease after surgery. Based on these findings, the tumour was diagnosed as a functional paraganglioma of the gall bladder. The patient has undergone regular thoracic radiographs and ultrasound examinations and, until 431 days after surgery, has shown no signs of metastases or recurrences. Based on our literature search, we report the first case of functional paraganglioma of the gall bladder in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37559209/