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Peer-reviewed veterinary case report

Large colon resection for treatment of lymphosarcoma in two horses.

Journal:
Journal of the American Veterinary Medical Association
Year:
1996
Authors:
Dabareiner, R M et al.
Affiliation:
Virginia-Maryland Regional College of Veterinary Medicine · United States
Species:
horse

Plain-English summary

In this study, two horses were treated for lymphosarcoma, which is a type of cancer affecting the blood system and can occur in the large intestine. These horses showed signs like mild belly pain that came and went, weight loss, fever, and blockages in the intestine due to the tumor pressing on it. Tests on the fluid in their abdomen showed either normal results or higher protein levels. If there were no signs that the cancer had spread to other areas, removing the affected part of the large intestine could help the horses live longer. The treatment was aimed at improving their condition and extending their survival.

Abstract

With the exception of lipoma, neoplasia of the gastrointestinal tract is rare in horses. Lymphosarcoma is the most common neoplasm of the hematopoietic system in horses. In horses with lymphosarcoma of the large colon, clinical signs may include intermittent signs of mild abdominal pain, weight loss, pyrexia, and pelvic flexure impaction caused by impingement of the colonic lumen by the mass. Peritoneal fluid analysis may be normal or have a high total protein concentration. If signs of metastasis are not evident, resection of the large colon affected by the mass may prolong survival.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/8617649/