Peer-reviewed veterinary case report
Fish oil effects on blood fats in female dogs with mammary cancer
By Costa-Santos, Keidylania et al.·Published in BMC veterinary research·2019·Escola de Medicina Veteriná, Brazil·View original on PubMed →
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Original publication title: Lipid and metabolic profiles in female dogs with mammary carcinoma receiving dietary fish oil supplementation.
- Species:
- dog
Plain-English summary
A group of overweight female dogs with mammary tumors were given dietary fish oil supplements to see if it would help their condition. The study found that these dogs had more aggressive tumors and higher levels of certain fats and proteins in their blood. While the fish oil did not change their fat levels, it did improve some metabolic markers like glucose and total protein. This suggests that while fish oil may not directly affect the tumors, it could help with some metabolic issues in dogs with cancer.
People also search for: dog mammary cancer treatment · fish oil for dogs with tumors · overweight dog cancer diet
Abstract
BACKGROUND: Dyslipidemias induce angiogenesis and accelerate the development and in vitro growth of breast tumors. The aim of this study was to assess the lipid and metabolic profile of female dogs with mammary carcinomas and their correlations with body condition score and degree of tumor malignancy, as well as to study the effect of dietary fish oil supplementation on these animals. RESULTS: Overweight or obese dogs had more aggressive carcinomas and higher triglyceride (p = 0.0363), VLDL (p = 0.0181), albumin (p = 0.0188), globulin (p = 0.0145) and lactate (p = 0.0255) concentrations. There was no change in the lipid profile after supplementation with fish oil at any concentration. However, in relation to the metabolic profile, glucose (p = 0.0067), total protein (p = 0.0002) and globulin (p = 0.0002) concentrations were increased when 90% omega-3 fish oil was used as a dietary supplement. CONCLUSION: Obese dogs showed altered lipid and metabolic profiles and more aggressive tumors, suggesting an important relationship between dyslipidemia and tumor aggressiveness. Supplementation with fish oil, rich in omega-3 fatty acids, may alter metabolic parameters in cancer patients.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31703601/