Peer-reviewed veterinary case report
Lymphoplasmacytic lymphoma in a stallion.
- Journal:
- The Journal of veterinary medical science
- Year:
- 1993
- Authors:
- Fukunaga, K et al.
- Affiliation:
- Chuo Meat Inspection Office · Japan
- Species:
- horse
Plain-English summary
A 6-year-old Anglo-Arabian stallion was diagnosed with lymphoplasmacytic lymphoma, a type of cancer affecting the immune system. The horse had a large mass in its chest and swollen lymph nodes throughout its body. The cancer cells were found to be at different stages of development, indicating they were related to B-cells, which are a part of the immune system. The tests showed specific characteristics of these cancer cells, helping to confirm the diagnosis. The outcome of the treatment is not mentioned, so it's unclear how well the stallion responded to any interventions.
Abstract
Lymphoplasmacytic lymphoma found in a 6-year-old Anglo-Arabian stallion was investigated histologically, immunohistochemically and ultrastructurally. The animal showed a large mediastinal mass and generalized lymph node involvement. The neoplastic cells were in various differentiation stages of small lymphocyte, centrocyte, centroblast, immunoblast and plasma cell. Some neoplastic cells showed positive cytoplasmic reactivity for mu and lambda chains. There were well developed rough endoplasmic reticulum (RER) and Golgi complexes in plasmacytoid cells, and slightly developed RER or a few long strands of RER in medium-sized to large lymphoid cells. These findings suggest that this neoplasm is of B-cell origin.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/8357923/