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Peer-reviewed veterinary case report

Lymphosarcoma with urinary bladder infiltration in a horse.

Journal:
Journal of the American Veterinary Medical Association
Year:
1991
Authors:
Sweeney, R W et al.
Affiliation:
Department of Clinical Studies · United States
Species:
horse

Plain-English summary

A 9-year-old Thoroughbred mare was taken to the vet because she had been urinating more often, had blood in her urine, and was losing weight for the past three weeks. During the exam, the vet found a soft tissue mass in her pelvic area and noticed some irregular heartbeats. Tests on her urine showed a lot of red blood cells and abnormal lymphocytes, which are a type of white blood cell often associated with cancer. Unfortunately, the horse was euthanized without any treatment, and a post-mortem examination revealed that the mass had spread into her bladder, vagina, and uterus, as well as other areas in her body. The final diagnosis was lymphosarcoma, a type of cancer.

Abstract

A 9-year-old Thoroughbred mare was examined because of pollakiuria, hematuria, and weight loss of 3 weeks' duration. Physical examination revealed a regular cardiac rhythm with occasional premature contractions, and a soft tissue mass in the pelvic canal palpable per rectum. Microscopic examination of urine sediment revealed numerous RBC and a large population of lymphocytes and lymphoblasts with characteristics of neoplasia. Similar cells were found in peritoneal fluid obtained by abdominocentesis. The horse was euthanatized without treatment. Necropsy revealed a soft tissue mass infiltrating the bladder, vagina, and uterus. Additional masses were found in the sublumbar muscles and myocardium. The histologic diagnosis was lymphosarcoma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/1752770/