Peer-reviewed veterinary case report
Dog with metastatic Leydig cell tumor treated with surgery and chemo
By Togni, A et al.·Published in Schweizer Archiv fur Tierheilkunde·2015·View original on PubMed →
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Original publication title: Metastasized Leydig cell tumor in a dog.
- Species:
- dog
Plain-English summary
An 11-year-old male Fox Terrier was diagnosed with a malignant Leydig cell tumor in his right testicle, which had spread to the muscles in his left hind leg. The tumor and the affected muscle were surgically removed, and the dog received chemotherapy with thalidomide and cyclophosphamide. Unfortunately, 30 months later, the cancer returned at the original site and had spread to the lungs, leading to the difficult decision to euthanize the dog.
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Abstract
We present the clinical findings, diagnosis and treatment of an 11-year old intact male Fox Terrier with a malignant Leydig cell tumor of the right testicle, which metastasized to the skeletal musculature of the left hind limb. The primary tumor and the metastasis were resected with narrow margins. The dog was treated with metronomic chemotherapy using thalidomid and dyclophosphamide. Local recurrence at the site of the metastasis and a pulmonary metastasis were present 30 months after surgery. The dog was euthanized.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26753337/