Peer-reviewed veterinary case report
Dog with colon and rectum tumors treated with surgery and chemo
By Trevor, P B et al.·Published in Journal of the American Veterinary Medical Association·1993·Department of Small Animal Clinical Sciences·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Metastatic extramedullary plasmacytoma of the colon and rectum in a dog.
- Species:
- dog
Plain-English summary
An 8-year-old Labrador Retriever was diagnosed with stage-3 extramedullary plasmacytoma, a type of cancer affecting the colon and rectum, along with metastasis to nearby lymph nodes and the spleen. The dog showed a spike in a specific protein in the blood, which is often linked to this condition. Treatment involved surgically removing the tumors and administering chemotherapy with melphalan and prednisone. Remarkably, nine months later, the dog showed no signs of the disease or side effects from the treatment, indicating a positive outcome.
People also search for: dog colon cancer treatment · Labrador Retriever cancer symptoms · chemotherapy for dog tumors
Abstract
Stage-3 extramedullary plasmacytoma of the large intestine was diagnosed in an 8-year-old Labrador Retriever. Three primary tumors were located in the colon and rectum, with metastasis to local lymph nodes and the spleen. The disease was associated with a monoclonal serum protein spike identified as IgG. Treatment consisted of surgical excision followed by chemotherapy, using melphalan and prednisone. The dog remained free from clinical signs of disease and adverse effects of the chemotherapy at 9 months. Findings in this dog indicated that extramedullary plasmacytoma may be an aggressive disease, associated with spread to distant sites and monoclonal gammopathy.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7693631/