Peer-reviewed veterinary case report
Dog with ovarian cancer spreading to small intestine surface
By Khaki, Fariba et al.·Published in Journal of ovarian research·2014·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Metastatic ovarian papillary cystadenocarcinoma to the small intestine serous surface: report of a case of high-grade histopathologic malignancy.
- Species:
- dog
Plain-English summary
A 7-year-old female mixed-breed dog was brought in with a growing mass in her abdomen, along with bloody discharge from her vulva and incontinence. After testing, the vet diagnosed her with a high-grade ovarian tumor that had spread to the lining of her small intestine. This type of cancer is aggressive and can be difficult to treat. Unfortunately, due to the advanced nature of the disease, the treatment options were limited, and the prognosis was poor.
People also search for: dog abdominal mass · dog bloody discharge from vulva · dog incontinence treatment · ovarian cancer in dogs · dog small intestine tumor
Abstract
Ovarian cystadenocarcinoma is characterized by marked heterogeneity and may be composed of an admixture of histologic growth patterns, including acinar, papillary and solid. In the present study, a case of isolated small intestine metastasis of ovarian papillary cystadenocarcinoma was reported. A 7-year-old female mixed-breed dog presented with a mass in the left upper quadrant with progressive enlargement of the abdomen, periodic bloody discharge from the vulva and incontinence. The tumor was histologically characterized by the presence of cysts and proliferation of papillae, both lined by single- or multi-layered pleomorphic epithelial cells. Furthermore, the mass was composed by intense cellular and nuclear pleomorphism and numerous mitotic figures. These findings indicate a tumor of high-grade malignancy with infiterative tumor cells resembling the papillary ovarian tumor in the serosal surface of the small intestine along with an intact serosa. Immunohistochemically, tumor was positive for CK7 and negative immunoreactivity for CK20. The histopathologic features coupled with the CK7 immunoreactivity led to a diagnosis of high grade ovarian papillary cystadenocarcinoma. To the best of our knowledge, this is the first case of small intestine serousal surface metastasis from ovarian papillary cystadenocarcinoma.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24636424/