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Peer-reviewed veterinary case report

Dog with nephrotic syndrome developing blood clots and clotting

By Ritt, M G et al.·Published in Journal of the American Animal Hospital Association·1997·Department of Small Animal Medicine and Surgery, United States·View original on PubMed

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Original publication title: Nephrotic syndrome resulting in thromboembolic disease and disseminated intravascular coagulation in a dog.

Species:
dog

Plain-English summary

A 5-year-old male Labrador was diagnosed with nephrotic syndrome, which led to serious complications including blood clots in the lungs and a dangerous condition called disseminated intravascular coagulation (DIC). The vet used various blood tests to check for clotting issues and confirmed the lung clots through imaging. Quick treatment was essential to manage these life-threatening problems. With appropriate care, the dog received the necessary treatment to address the complications from nephrotic syndrome.

People also search for: dog nephrotic syndrome symptoms · Labrador blood clot treatment · dog DIC management

Abstract

Thromboembolic disease and progression to disseminated intravascular coagulation (DIC) are potential life-threatening complications for dogs with nephrotic syndrome. Platelet count, prothrombin time (PT), activated partial thromboplastin time (APTT), plasma concentration of fibrinogen degradation products (FDPs), antithrombin III (ATIII), protein C, and plasminogen were used to identify hemostatic abnormalities in a dog with nephrotic syndrome. Pulmonary thromboembolic disease was diagnosed by thoracic radiography, arterial blood gas analysis, and pulmonary scintigraphy. Prompt recognition and treatment of hemostatic complications is necessary in dogs with nephrotic syndrome.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9278113/