Non-invasive and Locally Invasive Hypercellular Peripheral Odontogenic Fibroma in 20 Dogs.

Abstract

Medical records of dogs with an initial histopathological diagnosis of odontogenic sarcoma were reviewed for information on signalment, body weight, medical history, clinical signs, physical examination and diagnostic imaging findings, surgical procedure performed, and histologic characteristics. Twenty dogs were deemed to fit the criteria following the rigorous histology review process. These tumors were characterized by hypercellularity of the spindle cell component with less intervening stroma, mitotic activity, and variable presence of odontogenic epithelium and hard substance (cementum/dentin/bone). Non-invasive or locally invasive hypercellular peripheral odontogenic fibroma is suggested by the authors to describe these tumors. There were no signs of recurrence of any of the masses following surgical excisions with varying margins.