Peer-reviewed veterinary case report
Pet vomiting and lethargy after eating oclacitinib?
By Lister, Sara et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2025·ASPCA Animal Poison Control Center, United States·View original on PubMed →
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Original publication title: Oclacitinib Intoxication.
Plain-English summary
A dog or cat that accidentally eats too much of the chewable medication oclacitinib can show serious symptoms like vomiting, diarrhea, lethargy, and even heart problems. In some cases, pets may develop kidney issues or liver damage, which can be life-threatening. If your pet has ingested a large amount of this medication, it's crucial to seek veterinary help immediately. The vet may monitor your pet closely and provide treatments to manage the symptoms and prevent further complications.
People also search for: dog oclacitinib overdose symptoms · cat vomiting after medication · pet poisoning treatment · signs of kidney injury in dogs · what to do if my cat ate too much medicine
Abstract
BACKGROUND: Since the release of chewable flavored oclacitinib, household pets are ingesting larger quantities and are experiencing signs of toxicosis that have not been noted previously. KEY FINDINGS: Reports of intoxication have included gastrointestinal signs (vomiting, diarrhea, abdominal pain), cardiovascular signs (rhythm disturbances, hypotension, new onset heart murmur), CNS signs (lethargy, dull mentation, elevated nictitans), acute kidney injury in both dogs and cats, hepatotoxicity, and death. SIGNIFICANCE: When overdoses occur with meaningful clinical signs, clinicians are urged to provide proactive monitoring and treatment. Consultation with a poison control center and adverse event reporting to the manufacturer and the Food and Drug Administration are recommended.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40254916/